Native MS Guided Structural Biology Center

Surface-induced dissociation (SID) of protein complexes in a hybrid Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer.

Yan, J.; Zhou, M.; Gilbert, J. D. ; Wolff, J. J.; Somogyi, A.; Pedder, R. E.; Quintyn, R. S.; Morrison, L. J.; Easterling, M. L.; Paša-Tolić, L.; Wysocki , V. H.

Anal. Chem. 2017; DOI: 10.1021/acs.analchem.6b03986. Request reprint © (pdf)

Paper spray ionization of noncovalent protein complexes.

Zhang, Y.; Ju, Y.; Huang, C.; Wysocki, V.H.

Anal. Chem. 2014; 86(3):1342-6. Request reprint © (pdf)

Label-free detection and identification of protein ligands captured by receptors in a polymerized planar lipid bilayer using MALDI-TOF MS.

Liang, B.; Ju, Y.; Joubert, J. R.; Kaleta, E. J.; Lopez, R.; Jones, I. W.; Hall, H. K., Jr.; Ratnayaka, S. N.; Wysocki, V. H.; Saavedra, S. S.

Anal. Bioanal. Chem. 2015; Ahead of print. Request reprint © (pdf)

Transferrin Receptor Targeting by de Novo Sheet Extension.

Sahtoe, D. D.; Coscia, A.; Mustafaoglu, N.; Miller, L. M.; Olal, D.; Vulovic, I.; Yu, T.-Y.; Goreshnik, I.; Lin, Y.-R.; Clark, L.; Busch, F.; Stewart, L.; Wysocki, V. H.; Ingber, D. E.; Abraham, J.; Baker, D.

Proc Natl Acad Sci U S A 2021, 118 (17). https://doi.org/10.1073/pnas.2021569118.

Generation of Ordered Protein Assemblies Using Rigid Three-Body Fusion.

Vulovic, I.; Yao, Q.; Park, Y.-J.; Courbet, A.; Norris, A.; Busch, F.; Sahasrabuddhe, A.; Merten, H.; Sahtoe, D. D.; Ueda, G.; Fallas, J. A.; Weaver, S. J.; Hsia, Y.; Langan, R. A.; Plückthun, A.; Wysocki, V. H.; Veesler, D.; Jensen, G. J.; Baker, D.

Proc Natl Acad Sci U S A 2021, 118 (23), e2015037118. https://doi.org/10.1073/pnas.2015037118.

Molecular Assemblies of the Catalytic Domain of SOS with KRas and Oncogenic Mutants.

Moghadamchargari, Z.; Shirzadeh, M.; Liu, C.; Schrecke, S.; Packianathan, C.; Russell, D. H.; Zhao, M.; Laganowsky, A.

Proc Natl Acad Sci USA 2021, 118 (12), e2022403118. https://doi.org/10.1073/pnas.2022403118.

A polymetamorphic protein.

Stewart, K.L.; Dodds, E.D.; Wysocki, V.H.; Cordes, M.H.

Solution Structure of the Nucleotide Hydrolase BlsM: Implication of Its Substrate Specificity.

Kang, M.; Doddapaneni, K.; Sarni, S.; Heppner, Z.; Wysocki, V.; Wu, Z.

Protein Science 2020, 29 (8), 1760–1773. https://doi.org/10.1002/pro.3812

De Novo Design of Protein Logic Gates.

Chen, Z.; Kibler, R.D.; Hunt, A.; Busch, F.; Pearl, J.; Jia, M.; VanAernum, Z.L.; Wicky, B.I.M.; Dods, G.; Liao, H.; Wilken, M.S.; Ciarlo, C.; Green, S.; ElpSamad, H.; Stamatoyannopoulos, J.; Wysocki, V.H.; Jewett, M.C.; Boyken, S.E.; Baker, D.

Science, 03 April 2020, 368, 6486, 78-84. DOI: 10.1126/science.aay2790

De Novo Design of Tunable, pH-driven Conformational Changes.

Boyken, S.E.; Benhaim, M. A.; Busch, F.; Jia, M.; Bick, M. J.; Choi, H.; Klima, J. C.; Chen, Z.; Walkey, C.; Mileant, A.; Sahasrabuddhe, A.; Wei, K. Y.; Hodge, E. A.; Byron, S.; Quijano-Rubio, A.; Sankaran, B.; King, N. P.; Lippincott-Schwartz, J.; Wysocki, V. H.; Lee, K.K.; Baker D.

Science, 2019, 364(6441):658-664. DOI: 10.1126/science.aav7897.

Native MS Guided Structural Biology Center

Georgia Institute of Technology