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Mutant Poisoning Demonstrates a Nonsequential Mechanism for Digestion of Double-Stranded DNA by λ Exonuclease Trimers.

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:24
Pan, X.; Yan, J.; Patel, A.; Wysocki, V. H.; Bell, C. E.,

Biochemistry. 2015; 54 (3), 942-951. Request reprint © (pdf)

Structural Analysis of Activated SgrAI–DNA Oligomers Using Ion Mobility Mass Spectrometry.

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:24
Ma, X.; Shah, S.; Zhou, M.; Park, C. K.; Wysocki, V. H.; Horton, N. C.

Biochemistry. 2013; 52(25): 4373-81. Request reprint © (pdf)

Molecular model of a soluble guanylyl cyclase fragment determined by small-angle X-ray scattering and chemical cross-linking.

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:23
Fritz, B.G.; Roberts, S.A.; Ahmed, A.; Breci, L.; Li, W.; Weichsel, A.; Brailey, J.L.; Wysocki, V.H.; Tama, F.; Montfort, W.R.

Biochemistry-US. 2013; 52(9):1568-82. Request reprint © (pdf)

Structural Analysis of the Effect of Dual-FLAG Tag on Transthyretin.

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:23
Shirzadeh, M.; Poltash, M.L.; Laganowsky, A.; Russell, D.H.

Biochemistry, 2020, 59, 9, 1013-1022. DOI: 10.1021/acs.biochem.0c00105. 

A Disulfide-Stabilized Aβ That Forms Dimers but Does Not Form Fibrils.

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:22
Zhang, S.; Yoo, S.; Snyder, D. T.; Katz, B. B.; Henrickson, A.; Demeler, B.; Wysocki, V. H.; Kreutzer, A. G.; Nowick, J. S.

Biochemistry 2022. https://doi.org/10.1021/acs.biochem.1c00739.

Screening Tagged Proteins Using Tandem Affinity-Buffer Exchange Chromatography Online with Native Mass Spectrometry

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:21
Busch, F.; VanAernum, Z.; Lai, S. M.; Gopalan, V.; Wysocki, V.

Biochemistry 2021, 60 (24), 1876–1884. https://doi.org/10.1021/acs.biochem.1c00138.

Interfacial Residues Promote an Optimal Alignment of the Catalytic Center in Human Soluble Guanylate Cyclase: Heterodimerization Is Required but Not Sufficient for Activity.

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:21
Seeger, F.; Quintyn, R.; Tanimoto, A.; Williams, G.J.; Tainer, J.A.; Wysocki, V.H.; Garcin, E.D.

Biochem. 2014; 53(13), 2153-2165. Request reprint © (pdf)

Native Mass Spectrometry: Recent Progress and Remaining Challenges

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:20
Karch, K. R.; Snyder, D. T.; Harvey, S. R.; Wysocki, V. H.

Annual Review of Biophysics 2022, 51 (1). https://doi.org/10.1146/annurev-biophys-092721-085421.

Variable-Temperature Native Mass Spectrometry for Studies of Protein Folding, Stabilities, Assembly, and Molecular Interactions.

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:20
Laganowsky A, Clemmer DE, Russell DH.

Annu Rev Biophys. 2021 Dec 21. doi: 10.1146/annurev-biophys-102221-101121. Epub ahead of print. PMID: 34932911. 

Characterization of [2Fe‐2S]‐Cluster‐Bridged Protein Complexes and Reaction Intermediates by use of Robust Native Mass Spectrometric Methods.

Submitted by jlowe46@gatech.edu on Mon, 08/01/2022 - 14:19
Jia, M.; Sen, S.; Wachnowsky, C.; Fidai, I.; Cowan, J.A. and Wysocki, V.

Angewandte Chemie International Edition. 2020, DOI: 10.1002/anie.201915615 

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