Native MS Guided Structural Biology Center

Native MS Guided Structural Biology Center

Improving the Quadrupole to Ion Mobility Region in a Digital Quadrupole/Ion Mobility/Orbitrap Mass Spectrometer. J Am Soc Mass Spectrom. 2025 Nov 5;36(11):2389-2396. doi: 10.1021/jasms.5c00142. Epub 2025 Oct 2. PMID: 41037334

Schrader RL, Anderson GA, Evans KA, Russell DH.

Energy Resolved Mass Spectrometry Data from Surfaced Induced Dissociation Improves Prediction of Protein Complex Structure. Anal Chem. 2025 Feb 4;97(4):2375-2383. doi: 10.1021/acs.analchem.4c05837. Epub 2025 Jan 24. PMID: 39854242

Bolz RM, Seffernick JT, Drake ZC, Harvey SR, Wysocki VH, Lindert S.

Unveiling the Hidden: Dissecting Liraglutide Oligomerization Dual Pathways via Direct Mass Technology, Electron-Capture Dissociation, and Molecular Dynamics. Update in: Anal Chem. 2025 Jul 1;97(25):13465-13473. doi: 10.1021/acs.analchem.5c01851. PMID: 4

Kuo ST, Xi Z, Cong X, Yan X, Russell DH.

bioRxiv [Preprint]. 2025 Mar 4:2025.02.27.640645. doi: 10.1101/2025.02.27.640645.

Simultaneous ligand binding to intact and partially formed ATP binding sites in the hexameric termination factor Rho. bioRxiv [Preprint]. 2025 Jul 24:2025.07.22.665897. doi: 10.1101/2025.07.22.665897. Update in: J Biol Chem. 2025 Oct 9;301(12):110797. doi

Billings TD, Baker K, Lacey P, Muzquiz R, Wysocki VH, Foster MP.

bioRxiv [Preprint]. 2025 Jul 24:2025.07.22.665897. doi: 10.1101/2025.07.22.665897. Update in: J Biol Chem. 2025 Oct 9;301(12):110797. doi: 10.1016/j.jbc.2025.110797.

Design and Synthesis of Hetero-Bicephalic Detergents for Native Mass Spectrometry of Membrane Proteins. J Am Chem Soc. 2025 Aug 6;147(31):28513-28522. doi: 10.1021/jacs.5c10841. Epub 2025 Jul 25. PMID: 40709568

Chang JY, Azizov D, Shinde VN, Yun SD, Rider RL, Zhu Y, Bahramimoghaddam H, Lynn M, Russell DH, Fang L, Laganowsky A.

Hydration (H2O and D2O) Dictates the Stabilities and Conformational Entropy of Transthyretin Tetramers. J Am Chem Soc. 2025 Oct 1;147(39):35616-35626. doi: 10.1021/jacs.5c11055. Epub 2025 Sep 18. PMID: 40965130

Lantz C, Rider RL, Kuo ST, Xi Z, Burningham E, Yun SD, Laganowsky A, Russell DH.

Dissecting Hidden Liraglutide Oligomerization Pathways via Direct Mass Technology, Electron-Capture Dissociation, and Molecular Dynamics. Anal Chem. 2025 Jul 1;97(25):13465-13473. doi: 10.1021/acs.analchem.5c01851. Epub 2025 Jun 16. PMID: 40521838

Kuo ST, Xi Z, Cong X, Yan X, Russell DH.

Endogenous Aquaporin-0 Lipid Binding in Ocular Lens Tissue via Native Mass Spectrometry.J Am Soc Mass Spectrom. 2025 Aug 6;36(8):1588-1597. doi: 10.1021/jasms.4c00500. Epub 2025 Jun 24. PMID: 40554698

O'Neale CVT, Harvey SR, Chetyrkin S, Wysocki VH, Schey KL.

Molecular Basis for the Activation of Pseudomonas aeruginosa MsbA by Divalent Metals. J Am Chem Soc. 2025 Sep 3;147(35):31488-31496. doi: 10.1021/jacs.4c18759. Epub 2025 Aug 25. PMID: 40851428

Lyu J, Bahramimoghaddam H, Zhang T, Scott E, Yun SD, Yadav GP, Zhao M, Russell D, Laganowsky A.

Roles of Hydration in Protein-Ligand Binding: Passive or Active Participant? J Phys Chem A. 2025 Oct 9;129(40):9477-9485. doi: 10.1021/acs.jpca.5c04986. Epub 2025 Sep 30. PMID: 41026809

Evans KA, Sun HM, Powers M, Lantz C, Laganowsky A, Rye H, Russell DH.

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