Native MS Guided Structural Biology Center

Evaluation of a Bruker timsTOF Pro for Native Mass Spectrometry. ChemRxiv September 12, 2023. https://doi.org/10.26434/chemrxiv-2021-qr78t-v2.

Panczyk, E.; Lin, Y.-F.; Snyder, D.; Liu, F.; Ridgeway, M.; Park, M.; Bleiholder, C.; Wysocki, V.

Variation of CI-2 Conformers upon Addition of Methanol to Water: An IMS-MS-Based Thermodynamic Analysis. J. Phys. Chem. A 2023, 127 (45), 9399–9408. https://doi.org/10.1021/acs.jpca.3c03651.

Pan, H.; Raab, S. A.; El-Baba, T. J.; Schrecke, S. R.; Laganowsky, A.; Russell, D. H.; Clemmer, D. E.

PtuA and PtuB Assemble into an Inflammasome-like Oligomer for Anti-Phage Defense. Nat Struct Mol Biol 2024, 1–11. https://doi.org/10.1038/s41594-023-01172-8.

Li, Y.; Shen, Z.; Zhang, M.; Yang, X.-Y.; Cleary, S. P.; Xie, J.; Marathe, I. A.; Kostelic, M.; Greenwald, J.; Rish, A. D.; Wysocki, V. H.; Chen, C.; Chen, Q.; Fu, T.-M.; Yu, Y

Evaluation of Surface-Induced Dissociation Ion Mobility-Mass Spectrometry for Lipid Structural Characterization. J. Am. Soc. Mass Spectrom. 2024. https://doi.org/10.1021/jasms.3c00319.

Harris, R. A.; May, J. C.; Harvey, S. R.; Wysocki, V. H.; McLean, J. A.

Oxidized and Reduced Dimeric Protein Complexes Illustrate Contrasting CID and SID Charge Partitioning. J. Am. Soc. Mass Spectrom. 2023. https://doi.org/10.1021/jasms.3c00142.

Jia, M.; Song, Y.; Du, C.; Wysocki, V. H.

A Novel Y-Shaped, S–O–N–O–S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease. ACS Chem. Biol. 2023, 18 (3), 449–455. https://doi.org/10.1021/acschembio.2c00695.

Yang, K. S.; Blankenship, L. R.; Kuo, S.-T. A.; Sheng, Y. J.; Li, P.; Fierke, C. A.; Russell, D. H.; Yan, X.; Xu, S.; Liu, W. R.

Dissecting the Thermodynamics of ATP Binding to GroEL One Nucleotide at a Time. ACS Cent. Sci. 2023, 9 (3), 466–475. https://doi.org/10.1021/acscentsci.2c01065.

Walker, T.; Sun, H. M.; Gunnels, T.; Wysocki, V.; Laganowsky, A.; Rye, H.; Russell, D.

Serendipitous Discovery of a Competitive Inhibitor of FraB, a Salmonella Deglycase and Drug Target. Pathogens 2022, 11 (10), 1102. https://doi.org/10.3390/pathogens11101102.

Thirugnanasambantham, P.; Kovvali, S.; Cool, A.; Gao, Y.; Sabag-Daigle, A.; Boulanger, E. F.; Mitton-Fry, M.; Capua, A. D.; Behrman, E. J.; Wysocki, V. H.; Lindert, S.; Ahmer, B. M. M.; Gopalan, V.

Modified Ion Source for the Improved Collisional Activation of Protein Complexes. J Am Soc Mass Spectrom 2023, 34 (5), 977–980. https://doi.org/10.1021/jasms.3c00071.

Schrader, R. L.; Walker, T. E.; Russell, D. H.

Optimization of a Digital Mass Filter for the Isolation of Intact Protein Complexes in Stability Zone 1,1. Anal Chem 2023, 95 (5), 3062–3068. https://doi.org/10.1021/acs.analchem.2c05221.

Schrader, R. L.; Walker, T. E.; Chakravorty, S.; Anderson, G. A.; Reilly, P. T. A.; Russell, D. H.

Native MS Guided Structural Biology Center

Georgia Institute of Technology