Native MS Guided Structural Biology Center

Mass spectrometry Bound in flight.

Harvey, S. R.; Wysocki, V. H.

Nat. Chem. 2015; 7 (3), 189-190. Request reprint © (pdf)

De Novo Design of Tyrosine and Serine Kinase-Driven Protein Switches.

Woodall, N. B.; Weinberg, Z.; Park, J.; Busch, F.; Johnson, R. S.; Feldbauer, M. J.; Murphy, M.; Ahlrichs, M.; Yousif, I.; MacCoss, M. J.; Wysocki, V. H.; El-Samad, H.; Baker, D.

Nat Struct Mol Biol 2021, 28 (9), 762–770. https://doi.org/10.1038/s41594-021-00649-8.

How many human proteoforms are there?

Aebersold, R.; Agar, J. N.; Amster, I. J. A.; Baker, M. S. A.; Bertozzi, C. R.; Boja, E. S.; Costello, C. E.; Cravatt, B. F. A.; Fenselau, C.; Garcia, B. A.; Ge, Y.; Gunawardena, J.; Hendrickson, R. C.; Hergenrother, P. J.; Huber, C. G. A.; Ivanov, A. R.; Jensen, O. N.; Jewett, M. C.; Kelleher, N. L. A.; Kiessling, L. L. A.; Krogan, N. J.; Larsen, M. R.; Loo, J. A. A.; Ogorzalek Loo, R. R.; Lundberg, E.; MacCoss, M. J.; Mallick, P.; Mootha, V. K.; Mrksich, M.; Muir, T. W.; Patrie, S. M.; Pesaven

Nat Chem Biol. 2018; 14(3):206-214. DOI: 10.1038/nchembio.2576. Request reprint © (pdf)

Selective Regulation of Human TRAAK Channels by Biologically Active Phospholipids

Schrecke, S.; Zhu, Y.; McCabe, J. W.; Bartz, M.; Packianathan, C.; Zhao, M.; Zhou, M.; Russell, D.; Laganowsky, A.

Nat Chem Biol 2020, 1–7. https://doi.org/10.1038/s41589-020-00659-5.

Chemical and pathogen-induced inflammation disrupt the murine intestinal microbiome.

Borton, M. A.; Sabag-Daigle, A.; Wu, J.; Solden, L. M.; O’Banion, B. S.; Daly, R. A.;Wolfe, R. A.; Gonzalez, J. F.;Wysocki, V. H.; Ahmer, B. M. M.; Wrighton, K. C.

Microbiome. 2017; 5:47, DOI: 10.1186/s40168-017-0264-8. Request reprint © (pdf)

Use of Tandem Affinity-Buffer Exchange Chromatography Online with Native Mass Spectrometry for Optimizing Overexpression and Purification of Recombinant Proteins.

Lai, S.M.; Thirugnanasambantham, P.; Sidharthan, V.; Norris, A.S.; Law, J.D.; Gopalan, V.; Wyoscki, V.H.

Methods in Enzymology 2021, 659, 37-70. (Book chapter)

Purification, Reconstitution, and Mass Analysis of Archaeal RNase P, a Multisubunit Ribonucleoprotein Enzyme.

Zahurancik, W.J.; Norris, A.S.; Lai, S.M.; Snyder, D.T.; Wysocki, V.H.; Gopalan, V.

Methods in Enzymology, 2021, 659, 71-103. (Book chapter)

Biochemical Impact of a Disease-Causing Ile67Asn Substitution on BOLA3 Protein.

Sen, S.; Thompson, Z.; Wachnowsky, C.; Cleary, S.; Harvey, S. R.; Cowan, J. A.

Metallomics 2021, 13 (mfab010). https://doi.org/10.1093/mtomcs/mfab010.

The Ims Paradox: A Perspective on Structural Ion Mobility-Mass Spectrometry.

McCabe, J. W.; Hebert, M. J.; Shirzadeh, M.; Mallis, C. S.; Denton, J. K.; Walker, T. E.; Russell, D. H.

Mass Spectrometry Reviews 01 July 2020. https://doi.org/10.1002/mas.21642

Infrared Multiple-Photon Dissociation Action Spectroscopy of the b2+ Ion from PPG: Evidence of Third Residue Affecting b2+ Fragment Structure.

Poutsma, J. C.; Martens, J.; Oomens, J.; Maitre, P.; Steinmetz, V.; Bernier, M. C.; Jia, M.; Wysocki, V. H.

Journal of The American Society for Mass Spectrometry. 2017; 28: 1482-1488, DOI: 10.1007/s13361-017-1659-2. Request reprint © (pdf)

Native MS Guided Structural Biology Center

Georgia Institute of Technology