Center Publications: 2019-2023

Native MS Guided Structural Biology Center

Serendipitous Discovery of a Competitive Inhibitor of FraB, a Salmonella Deglycase and Drug Target. Pathogens 2022, 11 (10), 1102. https://doi.org/10.3390/pathogens11101102.

Thirugnanasambantham, P.; Kovvali, S.; Cool, A.; Gao, Y.; Sabag-Daigle, A.; Boulanger, E. F.; Mitton-Fry, M.; Capua, A. D.; Behrman, E. J.; Wysocki, V. H.; Lindert, S.; Ahmer, B. M. M.; Gopalan, V.

Modified Ion Source for the Improved Collisional Activation of Protein Complexes. J Am Soc Mass Spectrom 2023, 34 (5), 977–980. https://doi.org/10.1021/jasms.3c00071.

Schrader, R. L.; Walker, T. E.; Russell, D. H.

Optimization of a Digital Mass Filter for the Isolation of Intact Protein Complexes in Stability Zone 1,1. Anal Chem 2023, 95 (5), 3062–3068. https://doi.org/10.1021/acs.analchem.2c05221.

Schrader, R. L.; Walker, T. E.; Chakravorty, S.; Anderson, G. A.; Reilly, P. T. A.; Russell, D. H.

Digital Quadrupole Isolation and Electron Capture Dissociation on an Extended Mass Range Q-TOF Provides Sequence and Structure Information on Proteins and Protein Complexes.J Am Soc Mass Spectrom 2023, 34 (8), 1753–1760. https://doi.org/10.1021/jasms.3c00

Lantz, C.; Schrader, R.; Meeuwsen, J.; Shaw, J.; Goldberg, N. T.; Tichy, S.; Beckman, J.; Russell, D. H.

DJ-1 Molecular Chaperone Activity Depresses Tau Aggregation Propensity through Interaction with Monomers. Biochemistry 2023, 62 (5), 976–988. https://doi.org/10.1021/acs.biochem.2c00581.

Jimenez-Harrison, D.; Huseby, C. J.; Hoffman, C. N.; Sher, S.; Snyder, D.; Seal, B.; Yuan, C.; Fu, H.; Wysocki, V.; Giorgini, F.; Kuret, J.

In Situ Droplet-Based on-Tissue Chemical Derivatization for Lipid Isomer Characterization Using LESA. Anal Bioanal Chem 2023, 415 (18), 4197–4208. https://doi.org/10.1007/s00216-023-04653-3.

Freitas, D. P.; Chen, X.; Hirtzel, E. A.; Edwards, M. E.; Kim, J.; Wang, H.; Sun, Y.; Kocurek, K. I.; Russell, D.; Yan, X.

An Ion Mobility-Mass Spectrometry Study of Copper-Metallothionein-2A: Binding Sites and Stabilities of Cu-MT and Mixed Metal Cu–Ag and Cu–Cd Complexes. Analyst 2023, 148 (3), 546–555. https://doi.org/10.1039/D2AN01556K.

Fan, L.; Russell, D. H.

Combining Surface-Induced Dissociation and Charge Detection Mass Spectrometry to Reveal the Native Topology of Heterogeneous Protein Complexes. Anal. Chem. 2023, 95 (37), 13889–13896. https://doi.org/10.1021/acs.analchem.3c02185.

Du, C.; Cleary, S. P.; Kostelic, M. M.; Jones, B. J.; Kafader, J. O.; Wysocki, V. H.

Protein Structure Prediction with Mass Spectrometry Data. Annual Review of Physical Chemistry 2022, 73 (1), 1–19. https://doi.org/10.1146/annurev-physchem-082720-123928.

Biehn, S. E.; Lindert, S.

Predicting Ion Mobility Collision Cross Sections Using Projection Approximation with ROSIE-PARCS Webserver.

Turzo, S. M. B. A.; Seffernick, J. T.; Lyskov, S.; Lindert, S.

Briefings in Bioinformatics 2023, bbad308. https://doi.org/10.1093/bib/bbad308.

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Native MS Guided Structural Biology Center

Georgia Institute of Technology