A two-day short course in Native MS will be presented at ASMS 2021 on October 30-31, 2021.

Vicki Wysocki, Sophie Harvey, David Russell, and Arthur Laganowsky will serve as instructors. Topics include: Sample preparation for native MS; Membrane protein native MS; Instrumentation for nMS; Instrument conditions to keep soluble complexes native; Online separations approaches couples to nMS; Activation methods for nMS (non-covalent); Native-omics; Ion mobility instrumentation for nMS; Theoretical calculations and software for CCS determination; Intro to software tools and examples; Software tools demonstration; Variable temperature ESI; Thermodynamics and binding constants; Integrated platform and case studies.